In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials

This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials. With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.

About the Author

Toru Takebayashi Keio University Graduate School of Health Management Fujisawa, Kanagawa, Japan

Robert Landsiedel BASF SE Experimental Toxicology and Ecology Ludwigshafen am Rhein, Germany

Masashi Gamo National Institute of Advanced Industrial Science and Technology (AIST) Tsukuba, Ibaraki, Japan