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Maspin

Maspin

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About this ebook

This book represents the first compilation of the major research findings regarding Maspin a mammary serpin (or serine) protease inhibitor. Maspin was originally discovered through subtractive hybridization and differential display analyses, comparing the differences in gene expression in normal mammary epithelium and invasive carcinoma cells. This work originated in the laboratory of Dr. Ruth Sager, a world-renowned geneticist, at the Dana Farber Cancer Institute and Harvard Medical School. The first introduction of Maspin to the research community occurred as a report in Science (v263:526-529, 1994), and described the unique tumor-suppressing activity of this novel gene in human mammary epithelial cells.

About the Author

Mary J.C. Hendrix, Department of Anatomy and Cell Biology Holden Comprehensive Cancer Center The University of Iowa Iowa City, Iowa, U.S.A.

Author Mary J.C. Hendrix
ISBN-13 9781040194751
Publisher CRC Press
Publication Date 08/01/2002
Page Count 132 pages
Ebook details
Format
PDF
Language
English
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