Molecular Biology of Long Non-coding RNAs

This book examines key issues in lncRNA biology, including critical studies that have led to the discovery and annotation of lncRNAs in numerous species and the molecular mechanisms for a few lncRNA that have begun to emerge.

About the Author

Ahmad Khalil earned his PhD at the University of Florida School of Medicine where he discovered key epigenetic mechanisms that regulate gene expression during mammalian meiosis. Subsequently, he joined the Scripps Research Institute as a postdoctoral fellow (2006-2008) and studied the role of long non-coding RNAs in neurological disorders. In 2008, Dr Khalil moved to Harvard Medical School and the Broad Institute where he played a key role in discovering long intergenic non-coding (linc)RNAs in human cells, and demonstrated that lincRNAs play critical roles in epigenetic regulation of gene expression. In 2010, Dr Khalil joined the faculty at CWRU and his lab continues to study the role of lincRNAs in human health and disease.