Rabies: Scientific Basis of the Disease and its Management

Rabies is the most current and comprehensive account of one of the oldest diseases known that remains a significant public health threat despite the efforts of many who have endeavored to control it in wildlife and domestic animals. During the past five years since publication of the first edition there have been new developments in many areas on the rabies landscape. This edition takes on a more global perspective with many new authors offering fresh outlooks on each topic. Clinical features of rabies in humans and animals are discussed as well as basic science aspects, molecular biology, pathology, and pathogenesis of this disease. Current methods used in defining geographic origins and animal species infected in wildlife are presented, along with diagnostic methods for identifying the strain of virus based on its genomic sequence and antigenic structure. This multidisciplinary account is essential for clinicians as well as public health advisors, epidemiologists, wildlife biologists, and research scientists wanting to know more about the virus and the disease it causes.- Offers a unique global perspective on rabies where dog rabies is responsible for killing more people than yellow- More than 7 million people are potentially exposed to the virus annually and about 50,000 people, half of them children, die of rabies each year- New edition includes greatly expanded coverage of bat rabies which is now the most prominent source of human rabies in the New World and Western Europe, where dog rabies has been controlled- Recent successes of controlling wildlife rabies with an emphasis on prevention is discussed- Approximately 40% updated material incorporates recent knowledge on new approaches to therapy of human rabies as well as issues involving organ and tissue transplantation- Includes an increase in illustrations to more accurately represent this diseases' unique horror

About the Author

Dr. Alan C. Jackson is Adjunct Clinical Professor in the Department of Clinical Neurosciences (Neurology) at the University of Calgary in Calgary, Alberta, Canada. Previously, he was Professor of Medicine (Neurology) at Queen's University (Kingston, Ontario, Canada) and later at the University of Manitoba (Winnipeg, Manitoba, Canada). He graduated from Queen's University with BA and MD degrees. He completed an internship in internal medicine at University of Southern California, residencies in internal medicine at Queen's University and in neurology at the University of Western Ontario, and a fellowship in neurovirology at The Johns Hopkins University with Drs. Richard Johnson and Diane Griffin. Dr. Jackson has been active in rabies research for over 30 years.